Low density lipoprotein receptor related protein 6 (LRP6) protects heart against oxidative stress by the crosstalk of HSF1 and GSK3β

Low density lipoprotein receptor-related protein 6 (LRP6), a Wnt co-receptor, induces multiple functions in various organs. We recently reported cardiac specific LRP6 deficiency caused cardiac dysfunction in mice. Whether cardiomyocyte-expressed LRP6 protects hearts against ischemic stress is largel...

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Vydáno v:Redox Biol
Hlavní autoři: Wang, Ying, Chen, Zhidan, Li, Yang, Ma, Leilei, Zou, Yan, Wang, Xiang, Yin, Chao, Pan, Le, Shen, Yi, Jia, Jianguo, Yuan, Jie, Zhang, Guoping, Yang, Chunjie, Ge, Junbo, Zou, Yunzeng, Gong, Hui
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486456/
https://ncbi.nlm.nih.gov/pubmed/32905882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101699
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