Cardiomyocyte-Restricted Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) Deletion Leads to Lethal Dilated Cardiomyopathy Partly Through Drp1 Signaling

Low density lipoprotein receptor-related protein 6 (LRP6), a wnt co-receptor, regulates multiple functions in various organs. However, the roles of LRP6 in the adult heart are not well understood. Methods: We observed LRP6 expression in heart with end-stage dilated cardiomyopathy (DCM) by western bl...

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Vydáno v:Theranostics
Hlavní autoři: Chen, Zhidan, Li, Yang, Wang, Ying, Qian, Juying, Ma, Hong, Wang, Xiang, Jiang, Guoliang, Liu, Ming, An, Yanpeng, Ma, Leilei, Kang, Le, Jia, Jianguo, Yang, Chunjie, Zhang, Guoping, Chen, Ying, Gao, Wei, Fu, Mingqiang, Huang, Zheyong, Tang, Huiru, Zhu, Yichun, Ge, Junbo, Gong, Hui, Zou, Yunzeng
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2018
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771081/
https://ncbi.nlm.nih.gov/pubmed/29344294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.22177
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