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Elucidating the role of metal ions in carbonic anhydrase catalysis
Why metalloenzymes often show dramatic changes in their catalytic activity when subjected to chemically similar but non-native metal substitutions is a long-standing puzzle. Here, we report on the catalytic roles of metal ions in a model metalloenzyme system, human carbonic anhydrase II (CA II). Thr...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7486293/ https://ncbi.nlm.nih.gov/pubmed/32917908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18425-5 |
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