A CGRP receptor antagonist peptide formulated for nasal administration to treat migraine

OBJECTIVES: To investigate the formulation of the peptide-based antagonist ((34)Pro,(35)Phe)CGRP(27–37), of the human calcitonin gene-related peptide (CGRP) receptor as a potential nasally delivered migraine treatment. METHODS: Peptide sequences were prepared using automated methods and purified by...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Pharm Pharmacol
Prif Awduron: von Mentzer, Bengt, Russo, Andrew F, Zhang, Zhongming, Kuburas, Adisa, Killoran, Patrick M, D’Aloisio, Vera, Nizic, Laura, Capel, Vicky, Kendall, David A, Coxon, Christopher R, Hutcheon, Gillian A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2020
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486274/
https://ncbi.nlm.nih.gov/pubmed/32588458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jphp.13317
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