Convergent Evolution in Breadth of Two V(H)6-1-Encoded Influenza Antibody Clonotypes from a Single Donor

Understanding how broadly neutralizing antibodies (bnAbs) to influenza hemagglutinin (HA) naturally develop in humans is critical to the design of universal influenza vaccines. Several classes of bnAbs directed to the conserved HA stem were found in multiple individuals, including one encoded by hea...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Wu, Nicholas C., Andrews, Sarah F., Raab, Julie E., O’Connell, Sarah, Schramm, Chaim A., Ding, Xintao, Chambers, Michael J., Leung, Kwanyee, Wang, Lingshu, Zhang, Yi, Mascola, John R., Douek, Daniel C., Ledgerwood, Julie E., McDermott, Adrian B., Wilson, Ian A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486241/
https://ncbi.nlm.nih.gov/pubmed/32619441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2020.06.003
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