β-Catenin and Associated Proteins Regulate Lineage Differentiation in Ground State Mouse Embryonic Stem Cells

Mouse embryonic stem cells (ESCs) cultured in defined medium resemble the pre-implantation epiblast in the ground state, with full developmental capacity including the germline. β-Catenin is required to maintain ground state pluripotency in mouse ESCs, but its exact role is controversial. Here, we r...

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Publicado no:Stem Cell Reports
Main Authors: Tao, Fang, Soffers, Jelly, Hu, Deqing, Chen, Shiyuan, Gao, Xin, Zhang, Ying, Zhao, Chongbei, Smith, Sarah E., Unruh, Jay R., Zhang, Da, Tsuchiya, Dai, Venkatraman, Aparna, Zhao, Meng, Li, Zhenrui, Qian, Pengxu, Parmely, Tari, He, Xi C., Washburn, Michael, Florens, Laurence, Perry, John M., Zeitlinger, Julia, Workman, Jerry, Li, Linheng
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486223/
https://ncbi.nlm.nih.gov/pubmed/32822591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.07.018
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