Design and synthesis of fluorescent-methylphenidate analogues for FRET-based assay of Synapsin III binding

We previously described Synapsin III (Syn III) as a synaptic phosphoprotein that controls dopamine release in cooperation with alpha-synuclein (aSyn). Moreover, we found that in Parkinson’s disease (PD), Syn III also participates in alpha-synuclein (aSyn) aggregation and toxicity. Our recent observa...

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Detalhes bibliográficos
Publicado no:ChemMedChem
Main Authors: Casiraghi, Andrea, Longhena, Francesca, Straniero, Valentina, Faustini, Gaia, Newman, Amy H., Bellucci, Arianna, Valoti, Ermanno
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486004/
https://ncbi.nlm.nih.gov/pubmed/32452650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.202000128
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