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Antinociceptive effect of selective G protein-gated inwardly rectifying K(+) channel agonist ML297 in the rat spinal cord

The G protein-gated inwardly rectifying K(+) (GIRK) channels play important signaling roles in the central and peripheral nervous systems. However, the role of GIRK channel activation in pain signaling remains unknown mainly due to the lack of potent and selective GIRK channel activators until recen...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kimura, Masami, Shiokawa, Hiroaki, Karashima, Yuji, Sumie, Makoto, Hoka, Sumio, Yamaura, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7485804/
https://ncbi.nlm.nih.gov/pubmed/32915912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0239094
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