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Role of Glutathione Depletion and Reactive Oxygen Species Generation on Caspase-3 Activation: A Study With the Kinase Inhibitor Staurosporine

Oxidative stress is known to contribute to the progression of apoptosis. Staurosporine is a broad-spectrum inducer of apoptosis, but its mechanism of action is not well understood. The goal of the present work was to elucidate the role of glutathione and reactive oxygen species (ROS) in the executio...

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Detaylı Bibliyografya
Yayımlandı:Front Physiol
Asıl Yazarlar: Musaogullari, Aysenur, Mandato, Alysia, Chai, Yuh-Cherng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7485172/
https://ncbi.nlm.nih.gov/pubmed/32982774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00998
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