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A novel antimetabolite: TAS-102 for metastatic colorectal cancer

TAS-102 is a new oral anti-tumor drug, composed of a thymidine-based nucleoside analog (trifluridine: FTD) and a thymidine phosphorylase inhibitor (tipiracil hydrochloride: TPI). TAS-102 has been shown to significantly improve overall survival and progression-free survival in patients with refractor...

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Bibliografische gegevens
Gepubliceerd in:Expert Rev Clin Pharmacol
Hoofdauteurs: Miyamoto, Yuji, Lenz, Heinz-Josef, Baba, Hideo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7485169/
https://ncbi.nlm.nih.gov/pubmed/26677869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/17512433.2016.1133285
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