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TAS-102, a novel antitumor agent: a review of the mechanism of action
Inhibition of nucleoside metabolism is an important principle in cancer therapy as evidenced by the role of fluoropyrimidines, such as 5-fluorouracil (5-FU), and antifolates in the treatment of many cancers. TAS-102 is an oral combination therapy consisting of trifluridine (FTD), a thymidine-based n...
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| Publicado no: | Cancer Treat Rev |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4624296/ https://ncbi.nlm.nih.gov/pubmed/26428513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ctrv.2015.06.001 |
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