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PP2A Regulates Phosphorylation-Dependent Isomerization of Cytoplasmic and Mitochondrial-Associated ATR by Pin1 in DNA Damage Responses

Ataxia telangiectasia and Rad3-related protein (ATR) is a serine/threonine-protein kinase of the PI3K family and is well known for its key role in regulating DNA damage responses in the nucleus. In addition to its nuclear functions, ATR also was found to be a substrate of the prolyl isomerase Pin1 i...

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Dettagli Bibliografici
Pubblicato in:Front Cell Dev Biol
Autori principali: Makinwa, Yetunde, Cartwright, Brian M., Musich, Phillip R., Li, Zhengke, Biswas, Himadri, Zou, Yue
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484947/
https://ncbi.nlm.nih.gov/pubmed/32984322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00813
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