Induction of natural killer antibody-dependent cell cytotoxicity and of clinical activity of cetuximab plus avelumab in non-small cell lung cancer

BACKGROUND: Antibody-dependent cell-mediated cytotoxicity (ADCC) may mediate antitumour activity of IgG1-isotype monoclonal antibody (mAb), suggesting as potential treatment combination of IgG1-mAbs, anti-epidermal growth factor receptor cetuximab and anti-programmed death-ligand-1 avelumab. METHODS...

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Publicado en:ESMO Open
Autores principales: Fasano, Morena, Della Corte, Carminia Maria, Di Liello, Raimondo, Barra, Giusi, Sparano, Francesca, Viscardi, Giuseppe, Iacovino, Maria Lucia, Paragliola, Fernando, Famiglietti, Vincenzo, Ciaramella, Vincenza, Cimmino, Flora, Capasso, Mario, Iolascon, Achille, Sforza, Vincenzo, Morabito, Alessandro, Maiello, Evaristo, Ciardiello, Fortunato, Morgillo, Floriana
Formato: Artigo
Lenguaje:Inglês
Publicado: BMJ Publishing Group 2020
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484864/
https://ncbi.nlm.nih.gov/pubmed/32912860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/esmoopen-2020-000753
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