Induction of natural killer antibody-dependent cell cytotoxicity and of clinical activity of cetuximab plus avelumab in non-small cell lung cancer

BACKGROUND: Antibody-dependent cell-mediated cytotoxicity (ADCC) may mediate antitumour activity of IgG1-isotype monoclonal antibody (mAb), suggesting as potential treatment combination of IgG1-mAbs, anti-epidermal growth factor receptor cetuximab and anti-programmed death-ligand-1 avelumab. METHODS...

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Detalhes bibliográficos
Publicado no:ESMO Open
Main Authors: Fasano, Morena, Della Corte, Carminia Maria, Di Liello, Raimondo, Barra, Giusi, Sparano, Francesca, Viscardi, Giuseppe, Iacovino, Maria Lucia, Paragliola, Fernando, Famiglietti, Vincenzo, Ciaramella, Vincenza, Cimmino, Flora, Capasso, Mario, Iolascon, Achille, Sforza, Vincenzo, Morabito, Alessandro, Maiello, Evaristo, Ciardiello, Fortunato, Morgillo, Floriana
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484864/
https://ncbi.nlm.nih.gov/pubmed/32912860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/esmoopen-2020-000753
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