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Identification of colorectal cancers with defective DNA damage repair by immunohistochemical profiling of mismatch repair proteins, CDX2 and BRCA1

Colorectal cancer (CRC) is a complex disease as shown by consensus classification. The present study attempted to identify subtypes with known prognostic markers for better clinical management. A total of 72 CRC tumors were examined for the expression of mismatch repair (MMR) proteins, along with ca...

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Détails bibliographiques
Publié dans:Mol Clin Oncol
Auteurs principaux: Rajarajan, Savitha, C.E, Anupama, Jose, Betsy, Correa, Marjorie, Sengupta, Sagar, Prabhu, Jyothi S.
Format: Artigo
Langue:Inglês
Publié: D.A. Spandidos 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484731/
https://ncbi.nlm.nih.gov/pubmed/32953111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mco.2020.2128
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