Quantitation of iohexol, a glomerular filtration marker, in human plasma by LC-MS/MS

We developed a high-performance liquid chromatography mass spectrometry method for quantitating iohexol in 50 μL human plasma. After acetonitrile protein precipitation, chromatographic separation was achieved with a Shodex Asahipak NH2P-50 2D (5 μm, 2 × 150 mm) column and a gradient of 0.1% formic a...

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Detalhes bibliográficos
Publicado no:J Pharm Biomed Anal
Main Authors: Holleran, Julianne L., Parise, Robert A., Guo, Jianxia, Kiesel, Brian, Taylor, Sarah E., Ivy, S. Percy, Chu, Edward, Beumer, Jan H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484441/
https://ncbi.nlm.nih.gov/pubmed/32659569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2020.113464
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