Population-based screening for BRAF(V600E) in metastatic colorectal cancer reveals increased prevalence and poor prognosis

PURPOSE: BRAF(V600E) mutations portend poor prognosis in metastatic colorectal cancer (mCRC); however, the true prevalence and prognosis are unknown, as unwell patients may not undergo BRAF sequencing. PATIENTS AND METHODS: We reviewed a population-based cohort of 1898 patients with CRC that underwe...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Chu, Jenny E., Johnson, Benny, Kugathasan, Laveniya, Morris, Van K., Raghav, Kanwal P.S., Swanson, Lucas, Lim, Howard J., Renouf, Daniel J., Gill, Sharlene, Wolber, Robert, Karsan, Aly, Kopetz, Scott, Schaeffer, David F., Loree, Jonathan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484131/
https://ncbi.nlm.nih.gov/pubmed/32571791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-1024
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