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Whole-exome Sequencing (WES) Analysis of Alzheimer’s disease in Non-APOE*4 Carriers

The genetics of late-onset Alzheimer’s disease (AD) is complex due to the heterogeneous nature of the disorder. APOE*4 is the strongest genetic risk factor for AD. Genome-wide association studies have identified more than 30 additional loci, each having relatively small effect size. Known AD loci ex...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Fan, Kang-Hsien, Feingold, Eleanor, Rosenthal, Samantha L., Demirci, F. Yesim, Ganguli, Mary, Lopez, Oscar L., Kamboh, M. Ilyas
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484092/
https://ncbi.nlm.nih.gov/pubmed/32651314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-200037
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