Nalaganje...
Structural Basis of CD4 Downregulation by HIV-1 Nef
The HIV-1 Nef protein suppresses multiple immune surveillance mechanisms to promote viral pathogenesis and is an attractive target for the development of novel therapeutics. A key function of Nef is to remove the CD4 receptor from the cell surface by hijacking clathrin- and AP2-dependent endocytosis...
Shranjeno v:
| izdano v: | Nat Struct Mol Biol |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7483821/ https://ncbi.nlm.nih.gov/pubmed/32719457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-0463-z |
| Oznake: |
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