Posttranslational regulation of the exon skipping machinery controls aberrant splicing in leukemia

Splicing alterations are common in disease, such as cancer, where mutations in splicing factor genes are frequently responsible for aberrant splicing. Here we present an alternative mechanism for splicing regulation in T cell acute lymphoblastic leukemia (T-ALL), that involves posttranslational stab...

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Xehetasun bibliografikoak
Argitaratua izan da:Cancer Discov
Egile Nagusiak: Zhou, Yalu, Han, Cuijuan, Wang, Eric, Lorch, Adam H., Serafin, Valentina, Cho, Byoung-Kyu, Diaz, Blanca T. Gutierrez, Calvo, Julien, Fang, Celestia, Khodadadi-Jamayran, Alireza, Tabaglio, Tommaso, Marier, Christian, Kuchmiy, Anna, Sun, Limin, Yacu, George, Filip, Szymon K., Jin, Qi, Takahashi, Yoh-hei, Amici, David R., Rendleman, Emily J., Rawat, Radhika, Bresolin, Silvia, Paganin, Maddalena, Zhang, Cheng, Li, Hu, Kandela, Irawati, Politanska, Yuliya, Abdala-Valencia, Hiam, Mendillo, Marc L., Zhu, Ping, Palhais, Bruno, Van Vlierberghe, Pieter, Taghon, Tom, Aifantis, Iannis, Goo, Young Ah, Guccione, Ernesto, Heguy, Adriana, Tsirigos, Aristotelis, Wee, Keng Boon, Mishra, Rama K., Pflumio, Francoise, Accordi, Benedetta, Basso, Giuseppe, Ntziachristos, Panagiotis
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7483384/
https://ncbi.nlm.nih.gov/pubmed/32444465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-19-1436
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