Nuclear-mitochondrial communication involving miR-181c plays an important role in cardiac dysfunction during obesity

AIMS: In cardiomyocytes, there is microRNA (miR) in the mitochondria that originates from the nuclear genome and matures in the cytoplasm before translocating into the mitochondria. Overexpression of one such miR, miR-181c, can lead to heart failure by stimulating reactive oxygen species (ROS) produ...

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Detalhes bibliográficos
Publicado no:J Mol Cell Cardiol
Main Authors: Roman, Barbara, Kaur, Pawandeep, Ashok, Deepthi, Kohr, Mark, Biswas, Roopa, O’Rourke, Brian, Steenbergen, Charles, Das, Samarjit
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7483371/
https://ncbi.nlm.nih.gov/pubmed/32442661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2020.05.009
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