miR‐181c Activates Mitochondrial Calcium Uptake by Regulating MICU1 in the Heart

BACKGROUND: Translocation of miR‐181c into cardiac mitochondria downregulates the mitochondrial gene, mt‐COX1. miR‐181c/d(−/−) hearts experience less oxidative stress during ischemia/reperfusion (I/R) and are protected against I/R injury. Additionally, miR‐181c overexpression can increase mitochondr...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Am Heart Assoc
Egile Nagusiak: Banavath, Hemanth N., Roman, Barbara, Mackowski, Nathan, Biswas, Debjit, Afzal, Junaid, Nomura, Yohei, Solhjoo, Soroosh, O'Rourke, Brian, Kohr, Mark, Murphy, Elizabeth, Steenbergen, Charles, Das, Samarjit
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2019
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6951067/
https://ncbi.nlm.nih.gov/pubmed/31801413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.012919
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak