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Statins ameliorate cholesterol-induced inflammation and improve AQP2 expression by inhibiting NLRP3 activation in the kidney

Background: Chronic kidney diseases (CKD) are usually associated with dyslipidemia. Statin therapy has been primarily recommended for the prevention of cardiovascular risk in patients with CKD; however, the effects of statins on kidney disease progression remain controversial. This study aims to inv...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Kong, Yonglun, Feng, Weijing, Zhao, Xiaoduo, Zhang, Puhua, Li, Suchun, Li, Zhijian, Lin, Yu, Liang, Boen, Li, Chunling, Wang, Weidong, Huang, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7482822/
https://ncbi.nlm.nih.gov/pubmed/32929357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.49603
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