Antigen Recognition by MR1-Reactive T Cells; MAIT Cells, Metabolites, and Remaining Mysteries

Mucosal-associated Invariant T (MAIT) cells recognize vitamin B-based antigens presented by the non-polymorphic MHC class I related-1 molecule (MR1). Both MAIT T cell receptors (TCR) and MR1 are highly conserved among mammals, suggesting an important, and conserved, immune function. For many years,...

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發表在:Front Immunol
Main Authors: Corbett, Alexandra J., Awad, Wael, Wang, Huimeng, Chen, Zhenjun
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2020
主題:
Immunology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7482426/
https://ncbi.nlm.nih.gov/pubmed/32973800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01961
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