Switchable foldamer ion channels with antibacterial activity

Synthetic ion channels may have applications in treating channelopathies and as new classes of antibiotics, particularly if ion flow through the channels can be controlled. Here we describe triazole-capped octameric α-aminoisobutyric acid (Aib) foldamers that “switch on” ion channel activity in phos...

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Bibliografische gegevens
Gepubliceerd in:Chem Sci
Hoofdauteurs: Peters, Anna D., Borsley, Stefan, della Sala, Flavio, Cairns-Gibson, Dominic F., Leonidou, Marios, Clayden, Jonathan, Whitehead, George F. S., Vitórica-Yrezábal, Iñigo J., Takano, Eriko, Burthem, John, Cockroft, Scott L., Webb, Simon J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Royal Society of Chemistry 2020
Onderwerpen:
Chemistry
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7481839/
https://ncbi.nlm.nih.gov/pubmed/32953034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc02393k
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