Deficiency of the SMOC2 matricellular protein impairs bone healing and produces age-dependent bone loss

Secreted extracellular matrix components which regulate craniofacial development could be reactivated and play roles in adult wound healing. We report a patient with a loss-of-function of the secreted matricellular protein SMOC2 (SPARC related modular calcium binding 2) presenting severe oligodontia...

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Gepubliceerd in:Sci Rep
Hoofdauteurs: Morkmued, Supawich, Clauss, François, Schuhbaur, Brigitte, Fraulob, Valérie, Mathieu, Eric, Hemmerlé, Joseph, Clevers, Hans, Koo, Bon-Kyoung, Dollé, Pascal, Bloch-Zupan, Agnès, Niederreither, Karen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7481257/
https://ncbi.nlm.nih.gov/pubmed/32908163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71749-6
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