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Synthetic immunomodulation with a CRISPR super-repressor in vivo
Transient modulation of genes involved in immunity, without exerting a permanent change in the DNA code, can be an effective strategy to modulate the course of many inflammatory conditions. CRISPR-Cas9 technology represents a promising platform for achieving this goal. Truncation of guide RNA (gRNA)...
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| Pubblicato in: | Nat Cell Biol |
|---|---|
| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7480217/ https://ncbi.nlm.nih.gov/pubmed/32884147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-020-0563-3 |
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