The function of GORASPs in Golgi apparatus organization in vivo

In vitro experiments have shown that GRASP65 (GORASP1) and GRASP55 (GORASP2) proteins function in stacking Golgi cisternae. However, in vivo depletion of GORASPs in metazoans has given equivocal results. We have generated a mouse lacking both GORASPs and find that Golgi cisternae remained stacked. H...

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Udgivet i:J Cell Biol
Main Authors: Grond, Rianne, Veenendaal, Tineke, Duran, Juan M., Raote, Ishier, van Es, Johan H., Corstjens, Sebastiaan, Delfgou, Laura, El Haddouti, Benaissa, Malhotra, Vivek, Rabouille, Catherine
Format: Artigo
Sprog:Inglês
Udgivet: Rockefeller University Press 2020
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7480117/
https://ncbi.nlm.nih.gov/pubmed/32573693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202004191
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