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RAF1-activated MEK1 is found on the Golgi apparatus in late prophase and is required for Golgi complex fragmentation in mitosis

Amitotically activated mitogen-activated protein kinase 1 (MEK1) fragments the pericentriolar Golgi stacks in mammalian cells. We show that activated MEK1 is found on the Golgi apparatus in late prophase. The fragmented and dispersed Golgi membranes in prometaphase and later stages of mitosis do not...

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Autori principali: Colanzi, Antonino, Sutterlin, Christine, Malhotra, Vivek
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172875/
https://ncbi.nlm.nih.gov/pubmed/12695496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200208099
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