Discovery and Characterization of a Biologically Active Non–ATP-Competitive p38 MAP Kinase Inhibitor

Mitogen-activated protein kinase (MAPK) p38 is part of a broad and ubiquitously expressed family of MAPKs whose activity is responsible for mediating an intracellular response to extracellular stimuli through a phosphorylation cascade. p38 is central to this signaling node and is activated by upstre...

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Pubblicato in:J Biomol Screen
Autori principali: Wilson, Brice A. P., Alam, Muhammad S., Guszczynski, Tad, Jakob, Michal, Shenoy, Shilpa R., Mitchell, Carter A., Goncharova, Ekaterina I., Evans, Jason R., Wipf, Peter, Liu, Gang, Ashwell, Jonathan D., O’Keefe, Barry R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7480010/
https://ncbi.nlm.nih.gov/pubmed/26538432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057115615518
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