Proteomic Profiling of H-Ras-G12V Induced Hypertrophic Cardiomyopathy in Transgenic Mice Using Comparative LC-MS Analysis of Thin Fresh-Frozen Tissue Sections

Determination of disease-relevant proteomic profiles from limited tissue specimens, such as pathological biopsies and tissues from small model organisms, remains an analytical challenge and a much needed clinical goal. In this study, a transgenic mouse disease model of cardiac-specific H-Ras-G12V in...

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Pubblicato in:J Proteome Res
Autori principali: Wei, Bih-Rong, Simpson, R. Mark, Johann, Donald J., Dwyer, Jennifer E., Prieto, DaRue A., Kumar, Mia, Ye, Xiaoying, Luke, Brian, Shive, Heather R, Webster, Joshua D., Hoover, Shelley B., Veenstra, Timothy D., Blonder, Josip
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7480009/
https://ncbi.nlm.nih.gov/pubmed/22214408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr200612y
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