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Cord blood CD8(+) T-cell expansion following granulocyte transfusions eradicates refractory leukemia

The action of hematopoietic cell transplantation in controlling leukemia is principally mediated by donor T cells directed against residual recipient malignant cells. However, its utility is limited by graft-versus-host disease (GVHD), where alloreactivity is extended beyond leukemic and marrow cell...

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Bibliografiske detaljer
Udgivet i:Blood Adv
Main Authors: Hiwarkar, Prashant, Adams, Stuart, Gilmour, Kimberly, Nataraj, Ramya, Bonney, Denise, Poulton, Kay, Wynn, Robert
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7479944/
https://ncbi.nlm.nih.gov/pubmed/32886752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020001737
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