PI3Kδ inhibition reshapes follicular lymphoma–immune microenvironment cross talk and unleashes the activity of venetoclax

Despite idelalisib approval in relapsed follicular lymphoma (FL), a complete characterization of the immunomodulatory consequences of phosphatidylinositol 3-kinase δ (PI3Kδ) inhibition, biomarkers of response, and potential combinatorial therapies in FL remain to be established. Using ex vivo cocult...

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Dades bibliogràfiques
Publicat a:Blood Adv
Autors principals: Serrat, Neus, Guerrero-Hernández, Martina, Matas-Céspedes, Alba, Yahiaoui, Anella, Valero, Juan G., Nadeu, Ferran, Clot, Guillem, Di Re, Miriam, Corbera-Bellalta, Marc, Magnano, Laura, Rivas-Delgado, Alfredo, Enjuanes, Anna, Beà, Silvia, Cid, Maria C., Campo, Elías, Montero, Joan, Hodson, Daniel J., López-Guillermo, Armando, Colomer, Dolors, Tannheimer, Stacey, Pérez-Galán, Patricia
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2020
Matèries:
Lymphoid Neoplasia
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7479943/
https://ncbi.nlm.nih.gov/pubmed/32898249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020001584
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