Positive Role of the MHC Class-I Antigen Presentation Regulator m04/gp34 of Murine Cytomegalovirus in Antiviral Protection by CD8 T Cells

Murine cytomegalovirus (mCMV) codes for MHC class-I trafficking modulators m04/gp34, m06/gp48, and m152/gp40. By interacting with the MHC class-Iα chain, these proteins disconnect peptide-loaded MHC class-I (pMHC-I) complexes from the constitutive vesicular flow to the cell surface. Based on the ass...

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Bibliographische Detailangaben
Veröffentlicht in:Front Cell Infect Microbiol
Hauptverfasser: Becker, Sara, Fink, Annette, Podlech, Jürgen, Giese, Irina, Schmiedeke, Julia K., Bukur, Thomas, Reddehase, Matthias J., Lemmermann, Niels A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Cellular and Infection Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7479846/
https://ncbi.nlm.nih.gov/pubmed/32984075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2020.00454
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