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Nuclear deformation mediates liver cell mechanosensing in cirrhosis
BACKGROUND & AIMS: Liver stiffness is increased in advanced chronic liver disease (ACLD) and accurately predicts prognosis in this population. Recent data suggest that extracellular matrix stiffness per se may modulate the phenotype of liver cells. We aimed at investigating the effect of matrix...
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| Veröffentlicht in: | JHEP Rep |
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| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7479345/ https://ncbi.nlm.nih.gov/pubmed/32939447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhepr.2020.100145 |
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