Nuclear deformation mediates liver cell mechanosensing in cirrhosis

BACKGROUND & AIMS: Liver stiffness is increased in advanced chronic liver disease (ACLD) and accurately predicts prognosis in this population. Recent data suggest that extracellular matrix stiffness per se may modulate the phenotype of liver cells. We aimed at investigating the effect of matrix...

詳細記述

保存先:
書誌詳細
出版年:JHEP Rep
主要な著者: Guixé-Muntet, Sergi, Ortega-Ribera, Martí, Wang, Cong, Selicean, Sonia, Andreu, Ion, Kechagia, Jenny Z., Fondevila, Constantino, Roca-Cusachs, Pere, Dufour, Jean-François, Bosch, Jaime, Berzigotti, Annalisa, Gracia-Sancho, Jordi
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2020
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7479345/
https://ncbi.nlm.nih.gov/pubmed/32939447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhepr.2020.100145
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