miR-16-5p Suppresses Progression and Invasion of Osteosarcoma via Targeting at Smad3

BACKGROUND: MicroRNAs are known to regulate carcinogenesis of osteosarcoma. Although, miR-16-5p is known to exert inhibitory effects on several forms of cancers, its effects on the growth and invasion of osteosarcoma have not been studied. METHODS: We collected human osteosarcoma specimens and adjac...

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Publicado en:Front Pharmacol
Autores principales: Gu, Zhijian, Li, Zhikun, Xu, Ruijun, Zhu, Xiaodong, Hu, Ruixi, Xue, Yonghua, Xu, Wei
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7479212/
https://ncbi.nlm.nih.gov/pubmed/32982740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.01324
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