Synthetic Naphthofuranquinone Derivatives Are Effective in Eliminating Drug-Resistant Candida albicans in Hyphal, Biofilm, and Intracellular Forms: An Application for Skin-Infection Treatment

Candida albicans is the most common cause of fungal infection. The emergence of drug resistance leads to the need for novel antifungal agents. We aimed to design naphthofuranquinone analogs to treat drug-resistant C. albicans for topical application on cutaneous candidiasis. The time-killing respons...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Fang, Jia-You, Tang, Kai-Wei, Yang, Sien-Hung, Alalaiwe, Ahmed, Yang, Yu-Ching, Tseng, Chih-Hua, Yang, Shih-Chun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7479094/
https://ncbi.nlm.nih.gov/pubmed/32983038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.02053
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