Synthetic Naphthofuranquinone Derivatives Are Effective in Eliminating Drug-Resistant Candida albicans in Hyphal, Biofilm, and Intracellular Forms: An Application for Skin-Infection Treatment

Candida albicans is the most common cause of fungal infection. The emergence of drug resistance leads to the need for novel antifungal agents. We aimed to design naphthofuranquinone analogs to treat drug-resistant C. albicans for topical application on cutaneous candidiasis. The time-killing respons...

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Bibliographische Detailangaben
Veröffentlicht in:Front Microbiol
Hauptverfasser: Fang, Jia-You, Tang, Kai-Wei, Yang, Sien-Hung, Alalaiwe, Ahmed, Yang, Yu-Ching, Tseng, Chih-Hua, Yang, Shih-Chun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7479094/
https://ncbi.nlm.nih.gov/pubmed/32983038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.02053
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