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A perspective on HPK1 as a novel immuno-oncology drug target
In this perspective review, the role Hematopoietic Progenitor Kinase 1 (HPK1) in tumor immunity will be reviewed, with special emphasis on how T cells are negatively-regulated at different junctures of cancer-immunity cycle by this regulatory kinase. The review will highlight the strengths and weakn...
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| Publicado en: | eLife |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
eLife Sciences Publications, Ltd
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7478889/ https://ncbi.nlm.nih.gov/pubmed/32896273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55122 |
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