Longevity and replenishment of human liver-resident memory T cells and mononuclear phagocytes

The human liver contains specialized subsets of mononuclear phagocytes (MNPs) and T cells, but whether these have definitive features of tissue residence (long-term retention, lack of egress) and/or can be replenished from the circulation remains unclear. Here we addressed these questions using HLA-...

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Vydáno v:J Exp Med
Hlavní autoři: Pallett, Laura J., Burton, Alice R., Amin, Oliver E., Rodriguez-Tajes, Sergio, Patel, Amit A., Zakeri, Nekisa, Jeffery-Smith, Anna, Swadling, Leo, Schmidt, Nathalie M., Baiges, Anna, Gander, Amir, Yu, Dominic, Nasralla, David, Froghi, Farid, Iype, Satheesh, Davidson, Brian R., Thorburn, Douglas, Yona, Simon, Forns, Xavier, Maini, Mala K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Rockefeller University Press 2020
Témata:
Brief Definitive Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7478732/
https://ncbi.nlm.nih.gov/pubmed/32602903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20200050
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