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Design, synthesis, and SAR study of isopropoxy allylbenzene derivatives as 15-lipoxygenase inhibitors
OBJECTIVE(S): Allylbenzenes have been recently developed as inhibitors of lipoxygenases. They decrease peroxidation activity via mimicking 1,4-unsaturated bonds of fatty acids by their allyl portion. We designed and synthesized new derivatives of allyl benzenes (6a-f) with isopropoxy and amide subst...
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| Publicat a: | Iran J Basic Med Sci |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Mashhad University of Medical Sciences
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7478253/ https://ncbi.nlm.nih.gov/pubmed/32952943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2020.36793.8763 |
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