CD226 Attenuates Treg Proliferation via Akt and Erk Signaling in an EAE Model

Cluster of differentiation 226 (CD226) molecules play a crucial role in the activation of effector CD4(+) T cells during the immune response process, but a cell-intrinsic function of CD226 in CD4(+) T subsets is not clear. In this study, we showed that Cd226(−/−) mice were resistant to myelin oligod...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Wang, Ning, Yi, Hongyu, Fang, Liang, Jin, Jingyi, Ma, Qianli, Shen, Yuting, Li, Juan, Liang, Shuang, Xiong, Jie, Li, Zhuo, Zeng, Hanyu, Jiang, Fengliang, Jin, Boquan, Chen, Lihua
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7478170/
https://ncbi.nlm.nih.gov/pubmed/32983109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01883
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