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CD226 ligation protects against EAE by promoting IL-10 expression via regulation of CD4(+) T cell differentiation
Treatment targeting CD226 can ameliorate experimental autoimmune encephalomyelitis (EAE), the widely accepted model of MS. However, the mechanisms still need to be elucidated. Here we showed that CD226 blockage by anti-CD226 blocking mAb LeoA1 efficiently promoted IL-10 production in human periphera...
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| Wydane w: | Oncotarget |
|---|---|
| Główni autorzy: | , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Impact Journals LLC
2016
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4991380/ https://ncbi.nlm.nih.gov/pubmed/26942885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7834 |
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