CD226 ligation protects against EAE by promoting IL-10 expression via regulation of CD4(+) T cell differentiation

Treatment targeting CD226 can ameliorate experimental autoimmune encephalomyelitis (EAE), the widely accepted model of MS. However, the mechanisms still need to be elucidated. Here we showed that CD226 blockage by anti-CD226 blocking mAb LeoA1 efficiently promoted IL-10 production in human periphera...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Zhang, Rong, Zeng, Hanyu, Zhang, Yun, Chen, Kun, Zhang, Chunmei, Song, Chaojun, Fang, Liang, Xu, Zhuwei, Yang, Kun, Jin, Boquan, Wang, Qintao, Chen, Lihua
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2016
Konular:
Research Paper: Immunology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991380/
https://ncbi.nlm.nih.gov/pubmed/26942885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7834
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