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Indole compounds with N-ethyl morpholine moieties as CB2 receptor agonists for anti-inflammatory management of pain: synthesis and biological evaluation
The CB2 receptor plays a crucial role in analgesia and anti-inflammation. To develop novel CB2 agonists with high efficacy and selectivity, a series of indole derivatives with N-ethyl morpholine moieties (compounds 1–56) were designed, synthesized and biologically evaluated. Compounds 1, 2, 3, 46 an...
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| Vydáno v: | Medchemcomm |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Royal Society of Chemistry
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7478157/ https://ncbi.nlm.nih.gov/pubmed/32952995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00173e |
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