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Inhibition of Ciliogenesis Promotes Hedgehog Signaling, Tumorigenesis, and Metastasis in Breast Cancer

Primary cilia are chemosensors that play a dual role to either activate or repress Hedgehog signaling, depending on presence or absence of ligand respectively. While inhibition of ciliogenesis has been shown to be characteristic of breast cancers, the functional consequence is unknown. Here, for the...

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Bibliografske podrobnosti
izdano v:Mol Cancer Res
Main Authors: Hassounah, Nadia B., Nunez, Martha, Fordyce, Colleen, Roe, Denise, Nagle, Ray, Bunch, Thomas, McDermott, Kimberly M.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7478142/
https://ncbi.nlm.nih.gov/pubmed/28611083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0034
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