Loss of primary cilia occurs early in breast cancer development

BACKGROUND: Primary cilia are microtubule-based organelles that protrude from the cell surface. Primary cilia play a critical role in development and disease through regulation of signaling pathways including the Hedgehog pathway. Recent mouse models have also linked ciliary dysfunction to cancer. H...

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Dettagli Bibliografici
Autori principali: Menzl, Ina, Lebeau, Lauren, Pandey, Ritu, Hassounah, Nadia B, Li, Frank W, Nagle, Ray, Weihs, Karen, McDermott, Kimberly M
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076761/
https://ncbi.nlm.nih.gov/pubmed/24987519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2046-2530-3-7
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