Diffusion Tensor Imaging and Chemical Exchange Saturation Transfer MRI Evaluation on the Long-Term Effects of Pulsed Focused Ultrasound and Microbubbles Blood Brain Barrier Opening in the Rat

Blood-brain barrier opening (BBBO) with pulsed Focused Ultrasound (pFUS) and microbubbles (MB) has received increasing interest as a method for neurotherapeutics of the central nervous system. In general, conventional MRI [i.e., T2w, T2(∗)w, gadolinium (Gd) enhanced T1w] is used to monitor the effec...

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Опубликовано в: :Front Neurosci
Главные авторы: Tu, Tsang-Wei, Kovacs, Zsofia I., Sundby, Maggie, Witko, Jaclyn A., Papadakis, Georgios Z., Reid, William C., Hammoud, Dima A., Frank, Joseph A.
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2020
Предметы:
Neuroscience
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7478124/
https://ncbi.nlm.nih.gov/pubmed/32982680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.00908
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