In vivo imaging of sterile microglial activation in rat brain after disrupting the blood-brain barrier with pulsed focused ultrasound: [18F]DPA-714 PET study

BACKGROUND: Magnetic resonance imaging (MRI)-guided pulsed focused ultrasound combined with the infusion of microbubbles (pFUS+MB) induces transient blood-brain barrier opening (BBBO) in targeted regions. pFUS+MB, through the facilitation of neurotherapeutics’ delivery, has been advocated as an adju...

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Detalles Bibliográficos
Publicado en:J Neuroinflammation
Autores principales: Sinharay, Sanhita, Tu, Tsang-Wei, Kovacs, Zsofia I., Schreiber-Stainthorp, William, Sundby, Maggie, Zhang, Xiang, Papadakis, Georgios Z., Reid, William C., Frank, Joseph A., Hammoud, Dima A.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657093/
https://ncbi.nlm.nih.gov/pubmed/31345243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1543-z
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